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A
that
B
how
C
what
D
which
正确答案 :A
解析
【精析】A句意:由肺癌导致的大部分死亡是由抽烟引起的,这是一个事实。名词性从句题。分析句子结构可知,主句结构完整,所以空格后的句子应是一个作名词fact的同位语的从句,且从句不缺成分,只能用that,故本题选A。
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